Salmonella typhi the causative agent of typhoid, the consider largest killer disease is becoming a major threat due to emerging antimicrobial resistance. Mechanisms underlying bacterial drug resistance involve developing and/or acquiring of genetic elements in the form of variety of genes, gene complexes or mutations.These genetic elements are either chromosomal and/or extrachromosomal in the form of plasmids. The present study was conducted to investigation of the presence antibiotic-resistance genes (cat, dfrA7, gyrA, gyrB, strA-strB, sulI, sulII, tetB) were done by using PCR technique and electrophoresis systems. One hundred percent of S.typhi isolates were positive with gyrA, while 25 (83%) of isolates carry gyrB gene, 19 (63.3%) of isolates carry gene cat, dfrA7, 12(40%) and 6 (20%) isolates were carry sulII and sulI, respectively. Thirty (100%) of the isolates gave a negative genes results of (strA-strB, tetB).
Alkafeel University Achieves 3 Stars in QS Stars Ranking in 2023 snd scoring 5 Stars in Four Categories ( Click Here )
Al-Bahir Journal for Engineering and Pure Science Second Volume is Out! ( Click Here )
The Second Volume of Maaen Journal for Medical Science (MAJMS) is Published Online (Click Here)
University of Alkafeel Fifth International Conference ISCKU2024
Salmonella typhi the causative agent of typhoid, the consider largest killer disease is becoming a major threat due to emerging antimicrobial resistance. Mechanisms underlying bacterial drug resistance involve developing and/or acquiring of genetic elements in the form of variety of genes, gene complexes or mutations.These genetic elements are either chromosomal and/or extrachromosomal in the form of plasmids. The present study was conducted to investigation of the presence antibiotic-resistance genes (cat, dfrA7, gyrA, gyrB, strA-strB, sulI, sulII, tetB) were done by using PCR technique and electrophoresis systems. One hundred percent of S.typhi isolates were positive with gyrA, while 25 (83%) of isolates carry gyrB gene, 19 (63.3%) of isolates carry gene cat, dfrA7, 12(40%) and 6 (20%) isolates were carry sulII and sulI, respectively. Thirty (100%) of the isolates gave a negative genes results of (strA-strB, tetB).
